We are inviting you to take part in the CONNEX Studies, asking if a study medication, taken in addition to your current prescribed Schizophrenia medication, can improve cognition in people with Schizophrenia.
Cognitive symptoms are some of the core features of Schizophrenia. While antipsychotics are the primary medication for Schizophrenia, which work to reduce ‘psychotic’ symptoms, there is currently no approved medication for the treatment of the cognitive symptoms of Schizophrenia (trouble remembering, learning new things, concentrating, or making decisions). As such, these symptoms go largely untreated in many patients.
This is a phase 3 clinical trial, meaning the study medication has already been tested for the treatment of the cognitive symptoms in a smaller population of patients with Schizophrenia.
The CONNEX Studies will enroll patients from over 41 countries globally. Depending on which CONNEX Study you enroll in, you will visit a study center up to 16 times over up to 40 weeks. The studies involve taking a new study medication orally (by mouth), once daily.
There is no cost to take part in the CONNEX Studies. In addition, participants may receive reimbursement for time and travel expenses. No health insurance is required.
You may qualify for the CONNEX Studies if you:
- Are between the ages of 18 to 50 years old, inclusive
- Have been diagnosed with Schizophrenia
- Are currently taking an antipsychotic/Schizophrenia medication
- Experience cognitive symptoms which interfere with your day-to-day life such as difficulty following conversations or expressing yourself, trouble staying focused or difficulty remembering instructions or directions
There is no cost to participate in the study. All study-related care, including the study medication is provided at no cost.
Sign Up
What happens if I sign up? We will match you to a clinical trial location in your area that needs volunteers with Schizophrenia or notify you when one becomes available. The study team will then contact you and you may have the opportunity to participate if qualified.
If you think you might like to participate in the CONNEX Studies or would like more information, please enter your information below so we can see if you may qualify and can contact you about the studies. Keep in mind that participation is entirely voluntary. If you do decide to take part in a study, you may change your mind about participating at any time.
About Schizophrenia
Schizophrenia is a condition that affects people’s mental health in different ways.1,2 For example, it can affect a person’s mood or behaviour. It can also affect the way a person thinks, their memory and their mental functioning. Doctors call this ‘cognitive impairment’. Cognitive symptoms are some of the core features of Schizophrenia.
Examples of cognitive symptoms include:3
- Remembering where you put something
- Struggling to read a book or pay attention to a movie
- Calculating the correct change when you pay for something in cash
- Difficulty planning a journey so you arrive on time
Currently, there are no treatments for cognitive symptoms associated with Schizophrenia. That is why researchers are conducting the CONNEX Studies, three clinical trials that will research if a study medication can improve cognitive symptoms in people with Schizophrenia.
Frequently Asked Questions
What is a clinical trial?
A clinical trial (also called a research study) is a medical study that helps to answer important questions about an investigational drug – these may include how well an investigational study drug works for a certain condition. All medications must be tested in clinical research studies before they can be approved and prescribed to patients.
Why are clinical trials important?
A clinical trial is the process by which new and innovative medications, interventions and treatments are approved and brought to market, so people can live happier and healthier lives. Even over-the-counter medications, such as NSAIDs, you may have used to counteract a headache, have gone through the clinical research study process before it was available at your local pharmacy.
What is the purpose of the CONNEX Studies?
The CONNEX Studies are evaluating if a study medication, taken in addition to your current prescribed Schizophrenia medication, can improve some of the common cognitive symptoms of Schizophrenia (trouble remembering, learning new things, concentrating, or making decisions).
What will the CONNEX Studies involve?
The CONNEX Studies are asking if a study medication, taken in addition to your current antipsychotic medication, can improve cognition in people with Schizophrenia. This is a phase 3 clinical trial, meaning the study medication has already been tested for the treatment of the cognitive symptoms in a smaller population of patients with Schizophrenia.
The CONNEX Studies will enroll about 1758 participants with schizophrenia at study centers worldwide. Depending on which CONNEX Study you enroll in, you will visit a study center up to 16 times over up to 40 weeks. The studies involve taking a new study medication orally (by mouth), once daily.
Will I receive compensation?
Volunteers who qualify to take part in the study may receive reimbursement for time and travel expenses. Please discuss this with the study team when they contact you.
What else do I need to consider?
The research team will be able to explain more about what the CONNEX Studies will involve, and it is up to you to decide if you want to take part. Participation in this study is voluntary. Whether or not you decide to participate in this study will not affect your current or future relationships with your doctors. If you decide to participate, you are free to withdraw at any time without affecting those relationships.
How far is the study center?
We match you to a study center within a close travel distance from your home. If we are not running the study in your area currently, with your permission, we will keep you in our database and reach out once a study in your area becomes available. If, at any time, you decide you no longer want your information stored, you can opt out and we will delete your details.
About the CONNEX Studies
The CONNEX Studies will enroll about 1758 participants with Schizophrenia at study centers around the world. Depending on which CONNEX Study you enroll in, you will visit a study center up to 16 times over up to 40 weeks. The studies involve taking a new study medication orally (by mouth), once daily. There is no cost to take part in the CONNEX Studies. In addition, participants may receive reimbursement for time and travel expenses. No health insurance is required to participate. The CONNEX Studies are evaluating if a study medication, taken in addition to your current prescribed Schizophrenia medication, can improve some of the common cognitive symptoms of Schizophrenia (trouble remembering, learning new things, concentrating, or making decisions).
Who can take part in the CONNEX Studies?
You may qualify for the CONNEX Studies if you:
- Are between the ages of 18 to 50 years old, inclusive
- Have been diagnosed with Schizophrenia
- Are currently taking an antipsychotic/Schizophrenia medication
- Exhibit cognitive symptoms which interfere with your day-to-day life such as difficulty following conversations or expressing yourself, trouble staying focused or difficulty remembering instructions or directions